TAS2R60

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Protein-coding gene in the species Homo sapiens

TAS2R60
Identifiers
Aliases	TAS2R60, T2R56, T2R60, taste 2 receptor member 60
External IDs	OMIM: 613968; MGI: 2681302; HomoloGene: 52230; GeneCards: TAS2R60; OMA:TAS2R60 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q35 Start 143,443,453 bp[1] End 143,444,409 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B2.1 Start 42,382,368 bp[2] End 42,383,460 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad mucosa of large intestine mucosa of transverse colon blood cell white blood cell monocyte appendix liver placenta Top expressed in embryo granulocyte cerebellar cortex More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of bitter taste detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 338398 387512 Ensembl ENSG00000185899 ENSG00000285341 ENSMUSG00000056203 UniProt P59551 Q7TQA9 RefSeq (mRNA) NM_177437 NM_199159 RefSeq (protein) NP_803186 NP_954610 Location (UCSC) Chr 7: 143.44 – 143.44 Mb Chr 6: 42.38 – 42.38 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Taste receptor type 2 member 60 is a protein that in humans is encoded by the TAS2R60 gene.^[5][6]

See also

• Taste receptor

References

1. ^ ^{a b c} ENSG00000285341 GRCh38: Ensembl release 89: ENSG00000185899, ENSG00000285341 – Ensembl, May 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000056203 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.
6. ^ "Entrez Gene: TAS2R60 taste receptor, type 2, member 60".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
• Shi P, Zhang J, Yang H, Zhang YP (2004). "Adaptive diversification of bitter taste receptor genes in Mammalian evolution". Mol. Biol. Evol. 20 (5): 805–14. doi:10.1093/molbev/msg083. PMID 12679530.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

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