GPR22

In the world of GPR22, there is a wide range of opinions and perspectives that can be approached from different angles. From its impact on society to its relevance in history, GPR22 has been the subject of study and controversy over time. In this article, we will explore the various facets of GPR22, analyzing its influence in different contexts and its role in everyday life. Additionally, we will examine how GPR22 has evolved over time and what the future holds for it in an increasingly changing world. Through this exhaustive analysis, we aim to shed light on a topic that remains relevant and exciting to a wide spectrum of people.

Protein-coding gene in the species Homo sapiens

GPR22
Identifiers
Aliases	GPR22, G protein-coupled receptor 22
External IDs	OMIM: 601910; MGI: 1920260; HomoloGene: 18420; GeneCards: GPR22; OMA:GPR22 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.3 Start 107,470,018 bp[1] End 107,475,684 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 A3 Start 31,756,866 bp[2] End 31,763,946 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in superior frontal gyrus prefrontal cortex testicle dorsolateral prefrontal cortex Brodmann area 9 anterior cingulate cortex primary visual cortex right frontal lobe left ventricle hippocampus proper Top expressed in subiculum interventricular septum subdivision of hippocampus Region I of hippocampus proper hippocampus proper dentate gyrus lobe of cerebellum cerebellar vermis primary motor cortex piriform cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptide binding signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process cellular response to hormone stimulus signal transduction response to peptide G protein-coupled receptor signaling pathway cell projection organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2845 73010 Ensembl ENSG00000172209 ENSG00000283812 ENSMUSG00000044067 UniProt Q99680 Q3KNS9 Q8BZL4 RefSeq (mRNA) NM_005295 NM_175191 RefSeq (protein) NP_005286 NP_005286.2 NP_780400 Location (UCSC) Chr 7: 107.47 – 107.48 Mb Chr 12: 31.76 – 31.76 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 22 is a protein that in humans is encoded by the GPR22 gene.^[5][6]

References

1. ^ ^{a b c} ENSG00000283812 GRCh38: Ensembl release 89: ENSG00000172209, ENSG00000283812 – Ensembl, May 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000044067 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF Jr, Lynch KR, George SR (Apr 1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes". Gene. 187 (1): 75–81. doi:10.1016/S0378-1119(96)00722-6. PMID 9073069.
6. ^ "Entrez Gene: GPR22 G protein-coupled receptor 22".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lee J, Hever A, Willhite D, et al. (2006). "Effects of RNA degradation on gene expression analysis of human postmortem tissues". FASEB J. 19 (10): 1356–8. doi:10.1096/fj.04-3552fje. PMID 15955843. S2CID 3200625.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

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