AL-37350A

In this article, we will delve into the exciting world of AL-37350A, exploring its origins, its impact on current society and possible future implications. Since its emergence, AL-37350A has captured the attention of different audiences, generating debates, reflections and mixed emotions. Over the years, AL-37350A has demonstrated its influence in different areas, from technology to the arts, including politics and popular culture. Through a detailed analysis, we will seek to understand the relevance of AL-37350A in the contemporary world and its potential to transform the reality around us.

AL-37350A
Identifiers
  • (S)-(+)-1-(2-Aminopropyl)-8,9-dihydropyranoindole
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H18N2O
Molar mass230.311 g·mol−1
3D model (JSmol)
  • O2c1ccc3c(c1CCC2)c(c3)C(N)C
  • InChI=1S/C14H18N2O/c1-9(15)7-10-8-16-12-4-5-13-11(14(10)12)3-2-6-17-13/h4-5,8-9,16H,2-3,6-7,15H2,1H3/t9-/m0/s1 checkY
  • Key:VVHJUSGIUWQPIT-VIFPVBQESA-N checkY
 ☒NcheckY (what is this?)  (verify)

AL-37350A (4,5-DHP-AMT) is a tricyclic tryptamine derivative which acts as a potent and selective agonist for the serotonin receptor 5-HT2A, with a Ki of 2.0 nM, and moderate selectivity over the related 5-HT2B and 5-HT2C receptors. It has been shown to have ocular hypotensive activity in animal models, suggesting it may be useful for the treatment of glaucoma.[1]

See also

References

  1. ^ May JA, Chen HH, Rusinko A, Lynch VM, Sharif NA, McLaughlin MA (September 2003). "A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyranoindole". Journal of Medicinal Chemistry. 46 (19): 4188–95. CiteSeerX 10.1.1.688.6169. doi:10.1021/jm030205t. PMID 12954071.


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