WAY-208466

In today's article, we will explore the topic of WAY-208466 in depth. From its origins to its relevance in today's society, through its impact in different areas, we will immerse ourselves in an exhaustive analysis to understand the importance of WAY-208466 today. Additionally, we will examine various perspectives and opinions from experts in the field, with the goal of offering a complete and objective view of this highly relevant topic. Throughout the article, we will discover how WAY-208466 has evolved over time and what its possible implications are for the future. Get ready to embark on a fascinating journey through WAY-208466!

WAY-208466
Skeletal formula of WAY-208,466
Clinical data
ATC code
  • none
Identifiers
  • 2-{3--1H-pyrrolopyridin-1-yl}-N,N-dimethylethanamine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H18FN3O2S
Molar mass347.41 g·mol−1
3D model (JSmol)
  • CN(C)CCN1C=C(C2=C1N=CC=C2)S(=O)(=O)C3=CC=CC(=C3)F

WAY-208466 is a potent and highly selective full agonist of the 5-HT6 receptor.[1] It increases GABA levels in the cerebral cortex and tolerance does not appear to occur to this action upon chronic administration.[1] Animal studies have shown that WAY-208466 produces antidepressant and anxiolytic effects in rodents and it may also be useful in the treatment of obsessive-compulsive disorder.[1][2]

See also

References

  1. ^ a b c Schechter LE, Lin Q, Smith DL, et al. (May 2008). "Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466". Neuropsychopharmacology. 33 (6): 1323–35. doi:10.1038/sj.npp.1301503. PMID 17625499.
  2. ^ Carr GV, Schechter LE, Lucki I (March 2010). "Antidepressant and anxiolytic effects of selective 5-HT(6) receptor agonists in rats". Psychopharmacology. 213 (2–3): 499–507. doi:10.1007/s00213-010-1798-7. PMC 2910165. PMID 20217056.