Rescinnamine

In this article, we will explore the topic of Rescinnamine from different perspectives and approaches. Rescinnamine is a very important issue today, as it affects a wide spectrum of people and contexts. Over the next few lines, we will analyze the importance of Rescinnamine, its impact on society and some possible solutions or approaches to address this issue effectively. Through reflection and critical analysis, we will seek to better understand Rescinnamine and its relevance in everyday life.

Rescinnamine
rescinnamine 3D BS
Clinical data
Trade namesModeril, Cinnasil, Anaprel
Other namesmethyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-{oxy}-3,13-diazapentacyclohenicosa-2(10),4(9),5,7-tetraene-19-carboxylate
Routes of
administration
By mouth
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • methyl (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-{oxy}yohimban-16-carboxylate
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.042.232 Edit this at Wikidata
Chemical and physical data
FormulaC35H42N2O9
Molar mass634.726 g·mol−1
3D model (JSmol)
  • 26C(OC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1)(OC)(C(=O)OC)2()C5()c4c3cc(OC)ccc3c4CCN5C6
  • InChI=1S/C35H42N2O9/c1-40-21-8-9-22-23-11-12-37-18-20-15-29(46-30(38)10-7-19-13-27(41-2)33(43-4)28(14-19)42-3)34(44-5)31(35(39)45-6)24(20)17-26(37)32(23)36-25(22)16-21/h7-10,13-14,16,20,24,26,29,31,34,36H,11-12,15,17-18H2,1-6H3/b10-7+/t20-,24+,26-,29-,31+,34+/m1/s1 checkY
  • Key:SZLZWPPUNLXJEA-QEGASFHISA-N checkY
  (verify)

Rescinnamine, known by the brand names Moderil, Cinnasil, and Anaprel, is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.

It is an indoloquinolizine alkaloid similar to reserpine, obtained from Rauvolfia serpentina[1] and other species of Rauvolfia.[2]

References

  1. ^ FIFE R, MACLAURIN JC, WRIGHT JH (December 1960). "Rescinnamine in treatment of hypertension in hospital clinic and in general practice". British Medical Journal. 2 (5216): 1848–50. doi:10.1136/bmj.2.5216.1848. PMC 2098607. PMID 13699407.
  2. ^ Balsevich J, Constabel F, Kurz WG (1982). "Alkaloids of Vinca major cv. Variegata". Planta Med. 44 (2): 91–3. doi:10.1055/s-2007-971409. PMID 17402086.