LY-255582

In today's world, LY-255582 is a topic that has captured the attention of people of all ages and backgrounds. Whether due to its impact on society, its relevance in the professional field or its influence on popular culture, LY-255582 has positioned itself as a topic of general interest that generates all types of opinions and debates. From its origin to its possible consequences, LY-255582 has aroused the interest of academics, activists, opinion leaders and the general public, becoming an object of study and countless discussions. In this article, we will explore different aspects related to LY-255582 and its importance in today's world.

LY-255582
Names
Preferred IUPAC name
3-{(3R,4R)-1--3,4-dimethylpiperidin-4-yl}phenol
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1
    Key: LVVHEFJXPXAUDD-BULFRSBZSA-N
  • InChI=1/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1
    Key: LVVHEFJXPXAUDD-BULFRSBZBD
  • C1CN(CC1(C)C2=CC(=CC=C2)O)CC(C3CCCCC3)O
Properties
C22H35NO2
Molar mass 345.527 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).

LY-255582 is a phenylpiperidine non-selective opioid antagonist. It has been shown to reduce ethanol consumption in experiments carried out on rats.[1] It has also been shown to reduce food and water consumption in rats.[2]

See also

References

  1. ^ Dhaher R, et al. (Feb 2012). "Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats". Alcohol (Fayetteville, N.Y.). 46 (1): 17–27. doi:10.1016/j.alcohol.2011.08.011. PMC 4581853. PMID 21962974.
  2. ^ Shaw WN, et al. (Jun 1991). "The effect of the opioid antagonist LY255582 on body weight of the obese Zucker rat". International Journal of Obesity. 15 (6): 387–95. PMID 1653188.


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