Cannabidiorcol

In today's article we will explore the fascinating world of Cannabidiorcol. From its origins to its relevance today, Cannabidiorcol has been a topic of constant interest for researchers, academics and enthusiasts in general. Over the years, Cannabidiorcol has demonstrated its impact on different aspects of everyday life, whether in history, science, culture or technology. Through this article, we will delve into its many facets, with the aim of better understanding its influence on the world around us. Join us on this tour and discover everything Cannabidiorcol has to offer.

Cannabidiorcol
Identifiers
  • 5-methyl-2-benzene-1,3-diol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H22O2
Molar mass258.361 g·mol−1
3D model (JSmol)
  • CC1=C((CC1)C(=C)C)C2=C(C=C(C=C2O)C)O
  • InChI=1S/C17H22O2/c1-10(2)13-6-5-11(3)7-14(13)17-15(18)8-12(4)9-16(17)19/h7-9,13-14,18-19H,1,5-6H2,2-4H3/t13-,14+/m0/s1
  • Key:GKVOVXWEBSQJPA-UONOGXRCSA-N

Cannabidiorcol (CBDO, CBD-C1, O-1821) is a phytocannabinoid found naturally in Cannabis in trace concentrations. It is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors and is mainly active as an agonist of the TRPV2 cation channel, through which it produces antiinflammatory effects,[1] but can also promote tumorigenesis at high concentrations.[2]

See also

References

  1. ^ Laragione T, Harris C, Gulko PS (March 2023). "Combination therapy of a TRPV2 agonist with a TNF inhibitor achieves sustained suppression of disease severity and reduced joint damage". Clinical and Experimental Immunology. 211 (3): 233–238. doi:10.1093/cei/uxac124. PMC 10038320. PMID 36571199.
  2. ^ Huang R, Li S, Tian C, Zhou P, Zhao H, Xie W, et al. (November 2022). "Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma". British Journal of Cancer. 127 (8): 1424–1439. doi:10.1038/s41416-022-01896-2. PMC 9553907. PMID 35896815.