Morin (flavonol)

In today's world, Morin (flavonol) is a topic that has gained more and more relevance and interest in society. From its origins to its impact today, Morin (flavonol) has been the subject of debate, study and research by experts in different fields. Throughout history, Morin (flavonol) has demonstrated its influence in various aspects of everyday life, from politics to popular culture. In this article, we will explore the many facets of Morin (flavonol) and its importance in modern society, analyzing its implications and role in our world today.

Morin
Skeletal formula of morin
Ball-and-stick model of the morin molecule
Names
IUPAC name
2′,3,4′,5,7-Pentahydroxyflavone
Systematic IUPAC name
2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
Other names
Aurantica
Al-Morin
Morin hydrate
Calico Yellow
Toxylon pomiferum
Bois d'arc
Osage orange extract
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.006.858 Edit this at Wikidata
KEGG
  • InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H checkY
    Key: YXOLAZRVSSWPPT-UHFFFAOYSA-N checkY
  • InChI=1/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
    Key: YXOLAZRVSSWPPT-UHFFFAOYAH
  • O=C1c3c(O/C(=C1/O)c2ccc(O)cc2O)cc(O)cc3O
Properties
C15H10O7
Molar mass 302.238 g·mol−1
Density 1.799 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
checkY verify (what is checkY☒N ?)

Morin is a yellow chemical compound that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic), and from leaves of Psidium guajava (common guava).[1] In a preclinical in vitro study, morin was found to be a weak inhibitor of fatty acid synthase with an IC50 of 2.33 μM.[2] Morin was also found to inhibit amyloid formation by islet amyloid polypeptide (or amylin) and disaggregate amyloid fibers.[3]

Morin can be used to test for the presence of aluminium or tin in a solution, since it forms characteristically fluorescent coordination complexes with them under UV light.

Glycosides

References

  1. ^ a b c Rattanachaikunsopon, Pongsak; Phumkhachorn, Parichat (2007). "Bacteriostatic effect of flavonoids isolated from leaves of Psidium guajava on fish pathogens". Fitoterapia. 78 (6): 434–436. doi:10.1016/j.fitote.2007.03.015. PMID 17553634.
  2. ^ Tian, Wei-Xi (2006). "Inhibition of Fatty Acid Synthase by Polyphenols". Current Medicinal Chemistry. 13 (8): 967–977. doi:10.2174/092986706776361012. PMID 16611078.
  3. ^ Noor, Harris; Cao, Ping; Raleigh, Daniel P. (2012). "Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers". Protein Science. 21 (3): 373–382. doi:10.1002/pro.2023. PMC 3375438. PMID 22238175.


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