Trofosfamide

Today, Trofosfamide is a topic that arouses great interest in society. With the advancement of technology and globalization, Trofosfamide has become a fundamental element in people's lives. Its impact ranges from the economy, politics, culture, to the daily life of each individual. In this article we will explore the various facets of Trofosfamide and how it has changed over time. From its origins to its relevance in today's world, Trofosfamide is a topic that will continue to generate debate and controversy in the near future.

Trofosfamide
Skeletal formula of trofosfamide
Ball-and-stick model of the trofosfamide molecule
Clinical data
Trade namesIxoten
AHFS/Drugs.comInternational Drug Names
Routes of
administration		By mouth (film-coated tablets)
ATC code
Legal status
Legal status
  • DE: § 48 AMG/§ 1 MPAV (Prescription only)
Identifiers
  • N,N,3-tris(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amide 2-oxide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.040.686 Edit this at Wikidata
Chemical and physical data
FormulaC9H18Cl3N2O2P
Molar mass323.58 g·mol−1
3D model (JSmol)
  • C1CN(P(=O)(OC1)N(CCCl)CCCl)CCCl
  • InChI=1S/C9H18Cl3N2O2P/c10-2-6-13-5-1-9-16-17(13,15)14(7-3-11)8-4-12/h1-9H2 ☒N
  • Key:UMKFEPPTGMDVMI-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Trofosfamide (INN) is a nitrogen mustard alkylating agent. It is sometimes abbreviated "TRO".[1] It has been used in trials to study its effects on ependymoma, medulloblastoma, sarcoma, soft tissue,[clarification needed] supratentorial PNET, and recurrent brain tumors.[2]

References

  1. ^ Jahnke K, Thiel E, Bechrakis NE, et al. (December 2008). "Ifosfamide or trofosfamide in patients with intraocular lymphoma". J. Neurooncol. 93 (2): 213–7. doi:10.1007/s11060-008-9761-8. PMID 19099202. S2CID 33892177.
  2. ^ "Trofosfamide". www.drugbank.ca. Retrieved 2019-12-19.
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