Nedaplatin

Nowadays, Nedaplatin is a topic that has gained great relevance in today's society. In an increasingly globalized and connected world, Nedaplatin has become a topic of interest to a wide range of people. From professionals and academics to the general public, interest in Nedaplatin has been increasing and its importance has been reflected in various areas of daily life. Whether in the workplace, social, technological or cultural sphere, Nedaplatin has significantly impacted how we relate to and understand the world around us. In this article we will explore in detail the importance of Nedaplatin and its influence on today's society.

Nedaplatin
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		IV
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • Diammineplatinum
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC2H8N2O3Pt
Molar mass303.181 g·mol−1
3D model (JSmol)
  • C(C(=O)).N.N.

  • coordination form: O=C1O()()OC1
  • InChI=1S/C2H3O3.2H3N.Pt/c3-1-2(4)5;;;/h1H2,(H,4,5);2*1H3;/q-1;;;+2/p-1
  • Key:GYAVMUDJCHAASE-UHFFFAOYSA-M
  (verify)

Nedaplatin (INN, marketed under the tradename Aqupla) is a platinum-based antineoplastic drug which is used for cancer chemotherapy.[1] The complex consists of two ammine ligands and the dianion derived from glycolic acid.

Platinum-based drugs are widely employed as antineoplastic agents, especially cisplatin and carboplatin. Due to issues of their toxicity and number of cisplatin-resistant cancer cells, other platinum derivatives have been developed. Nedaplatin is one example of such new drugs.[2]

References

  1. ^ Apps MG, Choi EH, Wheate NJ (August 2015). "The state-of-play and future of platinum drugs". Endocrine-Related Cancer. 22 (4): R219-33. doi:10.1530/ERC-15-0237. hdl:2123/24426. PMID 26113607.
  2. ^ Johnstone TC, Park GY, Lippard SJ (January 2014). "Understanding and improving platinum anticancer drugs--phenanthriplatin". Anticancer Research. 34 (1): 471–6. PMC 3937549. PMID 24403503.
Stub icon

This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it.