Sercloremine

On this occasion, we want to address the topic of Sercloremine, which is undoubtedly a topic of great relevance today. Sercloremine is a topic that has sparked interest and debate in numerous areas, from the academic, scientific, political and social spheres. Throughout history, Sercloremine has played a fundamental role in the future of humanity, directly and indirectly affecting society as a whole. In this article, we will explore different perspectives and approaches on Sercloremine, analyzing its impact, evolution and relevance in different contexts. Without a doubt, Sercloremine is an exciting and complex topic that deserves to be approached from various points of view to understand its importance and impact in today's world.

Sercloremine
Names
Preferred IUPAC name
4-(5-Chloro-1-benzofuran-2-yl)-1-methylpiperidine
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C14H16ClNO/c1-16-6-4-10(5-7-16)14-9-11-8-12(15)2-3-13(11)17-14/h2-3,8-10H,4-7H2,1H3
    Key: FTKTZRKAVSDSRA-UHFFFAOYSA-N
  • CN1CCC(CC1)C2=CC3=C(O2)C=CC(=C3)Cl
Properties
C14H16ClNO
Molar mass 249.74 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).

Sercloremine (CGP-4718A), usually as the hydrochloride salt, is a drug which was developed in the 1980s and was formerly under investigation as an antidepressant, but was never marketed.[1][2] It acts as a selective, reversible inhibitor of monoamine oxidase A (RIMA) and serotonin reuptake inhibitor.[1][3]

References

  1. ^ a b Luttinger D, Hlasta DJ (January 1987). "Antidepressant agents". In Hesp B, Bailey DM (eds.). Annual Reports in Medicinal Chemistry. Vol. 22. Academic Press. pp. 21–30 (25). ISBN 978-0-08-058366-2.
  2. ^ Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1801–. ISBN 978-0-412-46630-4.
  3. ^ Delini-Stula A, Fischbach R, Gnirss F, Bures E, Pöldinger W (1985). "Early experience with CGP 4718 A (Sercloremine), a new selective and reversible MAO-A and 5-HT-uptake inhibitor, in the treatment of depressive patients". Drug Development Research. 6 (4): 371–384. doi:10.1002/ddr.430060409. ISSN 0272-4391. S2CID 85113482.


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