Metanephrine

Today we want to talk about Metanephrine, a topic that has gained great relevance in recent years. Metanephrine is a topic that has been the subject of debate, research and analysis in various areas, from politics to science, including culture and society in general. Metanephrine has raised conflicting opinions, generated controversy, been a source of discussion and has aroused the interest of many people. In this article, we will explore the different aspects of Metanephrine, delve into its importance, its implications and its influence in today's world. Without a doubt, Metanephrine is a topic that does not leave anyone indifferent and that deserves to be addressed in a deep and thoughtful manner.

This article is about Specific molecule "metanephrine". For Metanephrines group, see Metanephrines.
Metanephrine
Names
IUPAC name
4-(1-hydroxy-2-methylamino-ethyl)-2-methoxy-phenol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH Metanephrine
UNII
  • InChI=1S/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3 checkY
    Key: JWJCTZKFYGDABJ-UHFFFAOYSA-N checkY
  • InChI=1/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3
    Key: JWJCTZKFYGDABJ-UHFFFAOYAB
  • Oc1ccc(cc1OC)C(O)CNC
Properties
C10H15NO3
Molar mass 197.231 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
checkY verify (what is checkY☒N ?)

Metanephrine, also known as metadrenaline, is a metabolite of epinephrine (also known as adrenaline) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association, 2002, indicated that the measurement of plasma free levels of the metanephrines group of molecules (including metanephrine and normetanephrine) is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm.[1]

References

  1. ^ Lenders J, Pacak K, Walther M, Linehan W, Mannelli M, Friberg P, Keiser H, Goldstein D, Eisenhofer G (2002). "Biochemical diagnosis of pheochromocytoma: which test is best?". JAMA. 287 (11): 1427–34. doi:10.1001/jama.287.11.1427. PMID 11903030. Free full text with registration


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