Radequinil

In this article, we are going to delve into Radequinil, a topic that has aroused great interest in today's society. Radequinil is a concept that has gained relevance in various fields, from science to popular culture, and its influence has spread significantly in recent times. Along these lines, we will explore the different facets and dimensions of Radequinil, analyzing its impact on everyday life, its relevance in the academic field, as well as its presence in technology and entertainment. Through a multidisciplinary approach, we aim to shed light on Radequinil and offer a comprehensive view of this phenomenon that has captured the attention of numerous individuals and groups in contemporary society.

Radequinil
Clinical data
ATC code
  • None
Identifiers
  • 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H14N4O3
Molar mass334.335 g·mol−1
3D model (JSmol)
  • COc1cccc(c1)c3nccc2NC(=O)\C(=C/c23)c4nc(C)on4
  • InChI=1S/C18H14N4O3/c1-10-20-17(22-25-10)14-9-13-15(21-18(14)23)6-7-19-16(13)11-4-3-5-12(8-11)24-2/h3-9H,1-2H3,(H,21,23)
  • Key:JQOFKKWHXGQABB-UHFFFAOYSA-N

Radequinil (INN; AC-3933) is a cognitive enhancer which acts as a partial inverse agonist of the benzodiazepine site of the GABAA receptor.[1] It was under development by Dainippon Sumitomo Pharma for the treatment of Alzheimer's disease and made it to phase II clinical trials but development seems to have been halted and it was never marketed.[1][2]

See also

References

  1. ^ a b Martocchia A, Falaschi P (2008). "Current Strategies of Therapy in Alzheimer's Disease" (PDF). The Open Neuropsychopharmacology Journal. 1: 19–23. doi:10.2174/1876523800801010019.
  2. ^ Pogacić V, Herrling P (2007). "List of drugs in development for neurodegenerative diseases. Update June 2007". Neuro-Degenerative Diseases. 4 (6): 443–86. doi:10.1159/000107705. PMID 17934328.


Stub icon

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.