Lasinavir

In today's world, Lasinavir has become a topic of increasing interest to people of all ages and walks of life. Whether we are talking about Lasinavir on a personal, professional or social level, its importance and relevance are undeniable. From its origins to its impact today, Lasinavir has been the subject of debate, reflection and study by experts and enthusiasts alike. In this article, we will explore some of the most relevant and current aspects of Lasinavir, as well as its influence on our daily lives. Get ready to immerse yourself in the fascinating world of Lasinavir!

Lasinavir
Names
Systematic IUPAC name
tert-Butyl (3S,4S,6R,9S)-13-benzyl-12-hydroxy-6,9-dioxo-7-(propan-2-yl)-10--2-oxa-5,8,14-triazapentadecan-15-oate
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C35H53N3O9/c1-22(2)29(33(41)36-17-18-43-6)38-32(40)25(20-24-15-16-28(44-7)31(46-9)30(24)45-8)21-27(39)26(19-23-13-11-10-12-14-23)37-34(42)47-35(3,4)5/h10-16,22,25-27,29,39H,17-21H2,1-9H3,(H,36,41)(H,37,42)(H,38,40)/t25-,26+,27+,29+/m1/s1
    Key: BEUUJDAEPJZWHM-COROXYKFSA-N
  • CC(C)(C(=O)NCCOC)NC(=O)(CC1=C(C(=C(C=C1)OC)OC)OC)C((CC2=CC=CC=C2)NC(=O)OC(C)(C)C)O
Properties
C35H53N3O9
Molar mass 659.81 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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Lasinavir (INN,[1] previously known as BMS-234475 and CGP-61755) is an experimental peptidomimetic protease inhibitor researched by Novartis and Bristol-Myers Squibb as a treatment for HIV infection. It was originally discovered by Novartis at Basel (Switzerland).[2] Its investigation was terminated after Phase I on October 09, 2002.[3]

References

  1. ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). RECOMMENDED International Nonproprietary Names (Rec. INN): List 38" (PDF). WHO Drug Information. 11 (3). World Health Organization: 170. 1997. Retrieved 25 November 2015.
  2. ^ B2 US patent 7348345 B2, James Patrick Dunn, Steven Swallow, Zachary Kevin Sweeney, "Nonnucleoside reverse transcriptase inhibitors", issued 2008-08-02 
  3. ^ "Drug Profile: Lasinavir". AdisInsight. Adis International Ltd, part of Springer Science+Business Media. Retrieved 25 November 2015.
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