Fipravirimat

In this article we are going to delve into the fascinating world of Fipravirimat. From its origins and evolution to its relevance in today's society, we will explore all the aspects that make Fipravirimat a topic of interest and debate. We will learn about its different facets, its impact on our lives and its influence in the cultural and social sphere. Through a detailed analysis and a deep look, we will discover everything that Fipravirimat has to offer and how it has marked a before and after in history. Get ready to immerse yourself in this exciting journey and discover all the facets that make Fipravirimat a theme worth exploring.

Fipravirimat
Clinical data
Other namesGSK3640254
Legal status
Legal status
  • Investigational
Identifiers
  • (1R)-4--5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopentachrysen-9-yl]-1-(fluoromethyl)cyclohex-3-ene-1-carboxylic acid
CAS Number
PubChem CID
UNII
KEGG
Chemical and physical data
FormulaC43H67FN2O4S
Molar mass727.08 g·mol−1
3D model (JSmol)
  • CC(=C)1CC2(13CC4(3(CC2)C)(CC54(CC=C(C5(C)C)C6=CC(CC6)(CF)C(=O)O)C)C)NCCN7CCS(=O)(=O)CC7
  • InChI=1S/C43H67FN2O4S/c1-29(2)31-12-19-43(45-22-23-46-24-26-51(49,50)27-25-46)21-20-40(6)33(36(31)43)8-9-35-39(5)15-13-32(38(3,4)34(39)14-16-41(35,40)7)30-10-17-42(28-44,18-11-30)37(47)48/h10,13,31,33-36,45H,1,8-9,11-12,14-28H2,2-7H3,(H,47,48)/t31-,33+,34-,35+,36+,39-,40+,41+,42+,43-/m0/s1
  • Key:YFSNREBZTKMFEB-DHGHKPCRSA-N

Fipravirimat is an experimental drug for the treatment of HIV/AIDS. It belongs to a class of drugs known as maturation inhibitors.[1][2]

Fipravirimat was being developed by ViiV Healthcare, but development was stopped in 2023.[3]

See also

References

  1. ^ "Fipravirimat". PubChem. U.S. National Library of Medicine.
  2. ^ Dicker I, Jeffrey JL, Protack T, Lin Z, Cockett M, Chen Y, et al. (January 2022). "GSK3640254 Is a Novel HIV-1 Maturation Inhibitor with an Optimized Virology Profile". Antimicrobial Agents and Chemotherapy. 66 (1): e0187621. doi:10.1128/AAC.01876-21. PMC 8765437. PMID 34780263.
  3. ^ Waldron, James (2023-04-26). "GSK drops one of 2 maturation inhibitors in HIV pipeline". Retrieved 2023-09-18.
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