Diosmetin

In this article, we will explore the topic of Diosmetin in depth, examining its origins, evolution, and relevance today. From its impact on society to its influence on various aspects of our daily lives, Diosmetin has generated a great deal of interest and debate among experts and enthusiasts alike. Over the next few pages, we will explore the many facets of Diosmetin, analyzing its implications in areas as diverse as science, culture, politics and economics. Through a detailed and exhaustive approach, this article aims to offer a complete and up-to-date view on Diosmetin, providing readers with a deeper understanding of its importance in the contemporary world.

Diosmetin
Diosmetin structure
Diosmetin structure
Ball-and-stick model of diosmetin
Names
IUPAC name
3′,5,7-Trihydroxy-4′-methoxyflavone
Systematic IUPAC name
5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-benzopyran-4-one
Other names
Luteolin 4′-methyl ether
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.007.539 Edit this at Wikidata
UNII
  • InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3 ☒N
    Key: MBNGWHIJMBWFHU-UHFFFAOYSA-N ☒N
  • COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
Properties
C16H12O6
Molar mass 300.26 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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Diosmetin, also known as 5,7,3′-trihydroxy-4′-methoxyflavone, is an O-methylated flavone, a chemical compound that can be found in the Caucasian vetch.[1]

It has been found to act as a weak TrkB receptor agonist.[2]

Glycosides

Diosmetin is the aglycone of diosmin.

See also

References

  1. ^ Andreeva, O. A.; Ivashev, M. N.; Ozimina, I. I.; Maslikova, G. V. (1998). "Diosmetin glycosides from caucasian vetch: Isolation and study of biological activity". Pharmaceutical Chemistry Journal. 32 (11): 595–597. doi:10.1007/BF02465832. S2CID 21434373.
  2. ^ Jang SW, Liu X, Yepes M, Shepherd KR, Miller GW, Liu Y, Wilson WD, Xiao G, Blanchi B, Sun YE, Ye K (2010). "A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone". Proc. Natl. Acad. Sci. U.S.A. 107 (6): 2687–92. Bibcode:2010PNAS..107.2687J. doi:10.1073/pnas.0913572107. PMC 2823863. PMID 20133810.


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