Ampiroxicam

In this article we will explore the fascinating life of Ampiroxicam, whose experiences have left an indelible mark on history. From his humble beginnings to his rise to fame, Ampiroxicam has faced challenges and triumphs that have made him a symbol of inspiration to many. Throughout these pages, we will discover the most intimate details of his life, his impact on society, and his lasting legacy. Get ready to embark on a fascinating journey through the life of Ampiroxicam and discover the secrets behind his success.

Ampiroxicam
Structural formula of ampiroxicam
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • (RS)-Ethyl 1-thiazin-4-yl]oxyethyl carbonate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.235.757 Edit this at Wikidata
Chemical and physical data
FormulaC20H21N3O7S
Molar mass447.46 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3
  • InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24) checkY
  • Key:LSNWBKACGXCGAJ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Ampiroxicam (INN) is a non-steroidal anti-inflammatory drug (NSAID). It is a prodrug of piroxicam.[1] It has been studied for potential anticancer activity, but preliminary results did not show evidence of such activity.[2][3]

References

  1. ^ Carty TJ, Marfat A, Moore PF, Falkner FC, Twomey TM, Weissman A (July 1993). "Ampiroxicam, an anti-inflammatory agent which is a prodrug of piroxicam". Agents and Actions. 39 (3–4): 157–165. doi:10.1007/BF01998969. PMID 8304243. S2CID 24284281.
  2. ^ Choi KH, Shim JH, Huong LD, Cho NP, Cho SD (July 2011). "Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma". Oral Diseases. 17 (5): 469–475. doi:10.1111/j.1601-0825.2010.01774.x. PMID 21496182.
  3. ^ Shim JH, Shin JA, Jung JY, Choi KH, Choi ES, Cho NP, et al. (March 2011). "Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1". European Journal of Cancer Prevention. 20 (2): 102–111. doi:10.1097/CEJ.0b013e328341e38f. PMID 21131823.
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