8-OH-PBZI

The following article will address the topic of 8-OH-PBZI, which has currently generated great interest and debate. For a long time, 8-OH-PBZI has been the subject of study and analysis by experts in the area, and its impact has reached various spheres of society. On this occasion, we will seek to thoroughly analyze the most relevant aspects of 8-OH-PBZI, as well as address different perspectives that allow us to understand its importance and impact. Through a detailed and rigorous analysis, it is intended to offer a comprehensive view of 8-OH-PBZI, in order to provide the reader with a broad and complete understanding of this topic.

8-OH-PBZI
Clinical data
ATC code
  • none
Identifiers
  • (3aS,9bR)-3-propyl-1,2,3a,4,5,9b-hexahydrobenzoindol-8-ol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H21NO
Molar mass231.339 g·mol−1
3D model (JSmol)
  • CCCN1CC21CCC3=C2C=C(C=C3)O
  • InChI=1S/C15H21NO/c1-2-8-16-9-7-13-14-10-12(17)5-3-11(14)4-6-15(13)16/h3,5,10,13,15,17H,2,4,6-9H2,1H3/t13-,15+/m1/s1 checkY
  • Key:LJDRQPOQHHOXHM-HIFRSBDPSA-N checkY
  (verify)

8-OH-PBZI is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D3 receptor.[1][2][3]

References

  1. ^ Scheideler MA, Martin J, Hohlweg R, Rasmussen JS, Naerum L, Ludvigsen TS, et al. (November 1997). "The preferential dopamine D3 receptor agonist cis-8-OH-PBZI induces limbic Fos expression in rat brain". European Journal of Pharmacology. 339 (2–3): 261–70. doi:10.1016/S0014-2999(97)01372-1. PMID 9473144.
  2. ^ Fink-Jensen A, Nielsen EB, Hansen L, Scheideler MA (January 1998). "Behavioral and neurochemical effects of the preferential dopamine D3 receptor agonist cis-8-OH-PBZI". European Journal of Pharmacology. 342 (2–3): 153–61. doi:10.1016/S0014-2999(97)01494-5. PMID 9548380.
  3. ^ Malik P, Andersen MB, Peacock L (August 2004). "The effects of dopamine D3 agonists and antagonists in a nonhuman primate model of tardive dyskinesia". Pharmacology, Biochemistry, and Behavior. 78 (4): 805–10. doi:10.1016/j.pbb.2004.05.019. PMID 15301939. S2CID 19410897.
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