SIB-1553A

In today's world, SIB-1553A has become a topic of great importance and interest to a wide range of people. Whether due to its impact on society, the economy, culture or any other aspect of daily life, SIB-1553A plays a fundamental role in our reality. In this article, we will thoroughly explore the various facets of SIB-1553A and its influence in different areas. From its evolution over the years to its relevance today, through its relationship with other relevant topics, we will delve into a detailed analysis that will allow us to better understand the importance of SIB-1553A in today's world. Regardless of our background or particular interests, SIB-1553A is a topic that concerns us all and that deserves our attention and reflection.

SIB-1553A
Names
Preferred IUPAC name
4-{sulfanyl}phenol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C13H19NOS/c1-14-9-2-3-11(14)8-10-16-13-6-4-12(15)5-7-13/h4-7,11,15H,2-3,8-10H2,1H3
    Key: NVZGJSVPOOILDI-UHFFFAOYSA-N
  • InChI=1/C13H19NOS/c1-14-9-2-3-11(14)8-10-16-13-6-4-12(15)5-7-13/h4-7,11,15H,2-3,8-10H2,1H3
    Key: NVZGJSVPOOILDI-UHFFFAOYAV
  • OC1=CC=C(SCCC2CCCN2C)C=C1
Properties
C13H19NOS
Molar mass 237.36 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).

SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.[1]

References

  1. ^ Schneider, JS (July 2003). "The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys". Journal of Pharmacology and Experimental Therapeutics. 306 (1): 401–6. doi:10.1124/jpet.103.051912. PMID 12721323. S2CID 7060934.


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