Ribosome-nascent chain complex

This article will address the topic of Ribosome-nascent chain complex, an issue of great relevance and relevance in today's society. Ribosome-nascent chain complex has aroused great interest and debate in different areas, from the academic field to the political and social field. This issue has great complexity and diversity of approaches, which require a deep and exhaustive analysis. Throughout this article, different perspectives will be explored, contextualizing Ribosome-nascent chain complex within its historical and cultural framework, as well as examining its influence on various aspects of daily life. It is expected that this article contributes to the understanding and reflection on Ribosome-nascent chain complex, offering a comprehensive and critical vision of this topic of great relevance today.

Visualisation of an RNC showing the ribosome as a translucent cartoon and the nascent chain as a pink ribbon

Ribosome-nascent chain complex (RNC) refers to the collection of molecules that constitute a ribosome attached to the polypeptide (protein) that it is synthesising. The synthesis of the nascent polypeptide may be stalled by one of several methods. RNCs are produced and purified in laboratories to study the dynamics, biochemistry, folding and interactions of both the ribosome and proteins undergoing synthesis.[1][2]

References

  1. ^ Cabrita LD, Dobson CM, Christodoulou J (February 2010). "Protein folding on the ribosome". Current Opinion in Structural Biology. 20 (1): 33–45. doi:10.1016/j.sbi.2010.01.005. PMID 20149635.
  2. ^ Schaffitzel C, Ban N (June 2007). "Generation of ribosome nascent chain complexes for structural and functional studies". Journal of Structural Biology. 158 (3): 463–71. doi:10.1016/j.jsb.2007.01.005. PMID 17350284.
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