MMPIP

In this article we will explore the topic of MMPIP from various perspectives, with the aim of understanding its importance today. We will analyze its origins, evolution and repercussions on society, as well as its impact in different areas. Through a multidisciplinary approach, we will seek to delve deeper into the most relevant aspects of MMPIP, examining its implications in culture, economics, politics and other aspects of daily life. We will also delve into possible future trends related to MMPIP, in order to understand its long-term influence.

MMPIP
Identifiers
  • 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazolopyridin-4(5H)-one
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H19N3O3
Molar mass337.379 g·mol−1
3D model (JSmol)
  • COc3ccc(cc3)C2CC(C1C(=O)N2C)ON=C1c4ccncc4
  (verify)

MMPIP is a drug used in scientific research that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR7.[1] This receptor subtype appears to be involved in the downstream response to cocaine in the brain.[2]

References

  1. ^ Suzuki G, Tsukamoto N, Fushiki H, Kawagishi A, Nakamura M, Kurihara H, Mitsuya M, Ohkubo M, Ohta H (October 2007). "In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists". The Journal of Pharmacology and Experimental Therapeutics. 323 (1): 147–56. doi:10.1124/jpet.107.124701. PMID 17609420. S2CID 10402176.
  2. ^ Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX (June 2009). "Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism". Neuropsychopharmacology. 34 (7): 1783–96. doi:10.1038/npp.2008.236. PMC 3739975. PMID 19158667.


Stub icon

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.