Internal elastic lamina
In this article, we will explore in depth the topic of Internal elastic lamina and its implications in today's society. From its origins to its impact today, we will analyze the different aspects related to Internal elastic lamina and its relevance in different areas. Through careful research and analysis, we will seek to better understand the role Internal elastic lamina plays in our lives and how it influences the way we think, act, and relate to the world around us. Additionally, we will closely examine expert opinions and current trends regarding Internal elastic lamina, in order to provide a comprehensive and up-to-date view on this highly relevant topic.
The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels. It separates tunica intima from tunica media.
Histology
It is readily visualized with light microscopy in sections of muscular arteries, where it is thick and prominent, and arterioles, where it is slightly less prominent and often incomplete.[1] It is very thin in veins and venules.[1] In elastic arteries such as the aorta, which have very regular elastic laminae between layers of smooth muscle cells in their tunica media, the internal elastic lamina is approximately the same thickness as the other elastic laminae that are normally present.[2]
There is small amount of subendothelial connective tissue between basement membrane of endothelial cells and internal elastic lamina.[3]
Reduplication of internal elastic lamina can be seen in elderly individuals due to intimal fibroplasia, which is part of the aging process.[4]
Associated pathologic conditions
- Damage in giant cell arteritis leads to microaneurysms. Demonstration of fragmentation in this layer by elastin-van Gieson stain aids in diagnosis of giant cell arteritis. It stains muscle tissue in yellow, connective tissue in red and elastic structures (like internal elastic lamina) in black color.[4]
- In chronic allograft nephropathy, disruption or reduplication of internal elastic lamina can be observed, which causes narrowing of the lumen and downstream ischemia.[5]
- In fungal rhinosinusitis, the organism has predilection for internal elastic lamina during phase of spread.[6]
References
- ^ a b "Study and Revise Histology Online with Meyer's Histology".
- ^ "Cardiovascular System".
- ^ Histology Image Review. McGraw-Hill. 2007. pp. (Fig. 9–25).
- ^ a b Lee, K.Weng; Sehu, William R. (2005). Ophthalmic pathology : an illustrated guide for clinicians. Malden: Blackwell publishing. pp. 10, 98, 219. ISBN 9780727917799.
- ^ Clinical Nephrology Dialysis and Transplantation. Dustri-Verlag Feistle. 2004. pp. 21, 22 (of section III-5).
- ^ Zinreich, David W.; Kennedy, William E.; Bolger, S. James (2001). Diseases of the sinuses : diagnosis and management. Hamilton, Ont.: B.C. Decker. p. 192. ISBN 1-55009-045-3.