Clobetasol

Today, Clobetasol is a topic of great relevance and interest to a wide variety of people. From its origin and evolution to its impact on today's society, Clobetasol has become a point of interest and debate in different areas. Throughout history, Clobetasol has played a fundamental role in people's lives, influencing the way they think, act and relate. In this article, we will explore the different aspects related to Clobetasol, analyzing its importance and relevance today.

Clobetasol
Clinical data
Other names9α-Fluoro-11β,17α-dihydroxy-16β-methyl-21-chloropregna-1,4-diene-3,20-dione
Pregnancy
category
Drug classCorticosteroid; Glucocorticoid
ATC code
  • None
Identifiers
  • (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopentaphenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.042.379 Edit this at Wikidata
Chemical and physical data
FormulaC22H28ClFO4
Molar mass410.91 g·mol−1
3D model (JSmol)
  • C1C23CCC4=CC(=O)C=C4(3((C2(1(C(=O)CCl)O)C)O)F)C
  • InChI=1S/C22H28ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
  • Key:FCSHDIVRCWTZOX-DVTGEIKXSA-N

Clobetasol is a synthetic glucocorticoid corticosteroid. A propionate ester of clobetasol, clobetasol propionate, has also been marketed, and is far more widely used in comparison.[2][3]

References

  1. ^ "Updates to the Prescribing Medicines in Pregnancy database". Therapeutic Goods Administration (TGA). 21 December 2022. Archived from the original on 3 April 2022. Retrieved 2 January 2023.
  2. ^ Elks J, Ganellin CR, eds. (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 292–. doi:10.1007/978-1-4757-2085-3. ISBN 978-1-4757-2085-3.
  3. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 252–. ISBN 978-3-88763-075-1.