Arecaidine

In today's world, Arecaidine has gained great importance and interest, generating numerous discussions and research in different areas. Since its emergence, Arecaidine has significantly impacted society, the economy, culture and science, among other aspects. Over the years, Arecaidine has evolved and adapted to the different needs and demands of the current context, playing a crucial role in the development and transformation of various sectors. This is why it is relevant to thoroughly analyze and understand the impact and scope of Arecaidine today, as well as its future implications.

Chemical compound

Pharmaceutical compound

Arecaidine

Clinical data
Other names	Methylguvacine; Arecaine; N-Methylguvacine
Identifiers
IUPAC name 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid
CAS Number	499-04-7
PubChem CID	10355
IUPHAR/BPS	9487
ChemSpider	9928
UNII	0S8YEV0D4O
KEGG	C10128
ChEBI	CHEBI:2813
ChEMBL	ChEMBL432561
CompTox Dashboard (EPA)	DTXSID60198139
Chemical and physical data
Formula	C7H11NO2
Molar mass	141.170 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1CCC=C(C1)C(=O)O
InChI InChI=1S/C7H11NO2/c1-8-4-2-3-6(5-8)7(9)10/h3H,2,4-5H2,1H3,(H,9,10) Key:DNJFTXKSFAMXQF-UHFFFAOYSA-N

Arecaidine is a bio-active alkaloid in areca nuts.^[1] It is a competitive GABA reuptake inhibitor.^[2] Lime is said to hydrolyse arecoline to arecaidine^[2]

References

1. ^ Voigt V, Laug L, Zebisch K, Thondorf I, Markwardt F, Brandsch M (April 2013). "Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1)". The Journal of Pharmacy and Pharmacology. 65 (4): 582–590. doi:10.1111/jphp.12006. PMID 23488788. S2CID 27577546.
2. ^ ^{a b} Johnston GA, Krogsgaard-Larsen P, Stephanson A (December 1975). "Betel nut constituents as inhibitors of gamma-aminobutyric acid uptake". Nature. 258 (5536): 627–628. Bibcode:1975Natur.258..627J. doi:10.1038/258627a0. PMID 1207742. S2CID 4147760.