In this article, we will explore ALDH8A1 from various angles and perspectives with the aim of thoroughly understanding its importance, impact and relevance in the current context. We will highlight the different facets and dimensions of ALDH8A1, examining its influence in various fields and its interaction with other elements that shape our reality. Through a detailed and exhaustive analysis, we will reveal the complexity and depth of ALDH8A1, offering a comprehensive vision that allows us to fully appreciate its meaning. Using a holistic approach, we will approach ALDH8A1 from a multifaceted perspective, inviting the reader to immerse themselves in a journey of discovery and understanding that broadens their horizons and enriches their knowledge on this topic.
Protein-coding gene in the species Homo sapiens
Aldehyde dehydrogenase 8 family, member A1 also known as ALDH8A1 is an enzyme that in humans is encoded by the ALDH8A1 gene.[5]
Function
This protein belongs to the aldehyde dehydrogenase family of enzymes. It was originally thought to play a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. However, bioinformatics and experimental work has shown that it is more likely the aldehyde dehydrogenase of the kynurenine pathway, oxidizing 2-aminomuconate semialdehyde to 2-aminomuconic acid.[6] Two transcript variants encoding distinct isoforms have been identified for this gene.[7]
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
